Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Although the substance has not been tested experimentally for bio-accumulation / bio-concentration, it can be reasonably assumed that TGMDA is neither bio-accumulative nor bio-concentrating, based on the following observations snf calculations:

The calculated logPow is low (2.12 in an experimental study, and 2.53, calculated by ECOSAR), and based on comparative data from Bisphenol-A diglycidyl ether and triglycidyk isovyanurate the hydrolysis half-life is expected to be 7 - 15 days in water, but much faster in cold- and warm-blooded animals, in which epoxide hydrolases are present. Hydrolised TGMDA is expected to be rapidly eliminated by glucuronidation and subsequent elimination via urine, or by sulfation and excretion via urine or bile.