Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
4-nitro-o-anisidine
Status:
67/548/EEC self classification
Remarks:
The substance is self-classified as R40 derived from tumor formation in a feeding test of rats with the structural isomer 2-methoxy-5-nitroaniline (Lit. Berufsgenossenschaft der Chemischen Industrie, issue 12/95).

Related composition

Related composition:
Composition 2

Classification

Explosiveness

Reason for no classification:
conclusive but not sufficient for classification

Oxidising properties

Reason for no classification:
conclusive but not sufficient for classification

Flammability

Reason for no classification:
conclusive but not sufficient for classification

Thermal stability

Reason for no classification:
conclusive but not sufficient for classification

Acute toxicity

Classification:
Xn; R22 Harmful if swallowed.

Acute toxicity - irreversible damage after single exposure

Reason for no classification:
conclusive but not sufficient for classification

Repeated dose toxicity

Reason for no classification:
data lacking

Irritation / corrosion

Reason for no classification:
conclusive but not sufficient for classification

Sensitisation

Reason for no classification:
conclusive but not sufficient for classification

Carcinogenicity

Classification:
Carc. Cat. 3; R40 Limited evidence of a carcinogenic effect.

Mutagenicity - genetic toxicity

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - fertility

Reason for no classification:
data lacking

Toxicity to reproduction - development

Reason for no classification:
data lacking

Toxicity to reproduction - breastfed babies

Reason for no classification:
data lacking

Environment

Classification:
N; R51/53 Dangerous for the environment; Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Labelling

Indication of danger

N - dangerous for the environment
Xn - harmful

Risk phrases

R22 - Harmful if swallowed
R40 - Limited evidence of a carcinogenic effect
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment

Safety phrases

S22 - do not breathe dust
S36/37 - wear suitable protective clothing and gloves
S61 - avoid release to the environment. refer to special instructions/safety data sheets

Specific concentration limits

Notes