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Justification for Read Across

Attached at section 13 is a category justification that explains the rationale for using data on a mixture of Dimethyl Esters (DBE), and Dimethyl Glutarate, to supplement the available data on Dimethyl Adipate.

Short term tests with species of 3 trophic levels are available. Fish is the most sensitive species with an LC50 (96h) which ranges between a NOEC of 18 ppm and a LOEC of 24 ppm. Short-term effects of the substance towards daphnia and algae were found greater than 112 ppm and greater than 85 mg/l respectively.