Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Readily biodegradable: 84.6%  (CO2 evolution) in 28 days (OECD 301B)

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

Two studies investigating the ready biodegradability Bis(2-ethylhexyl) sebacate (CAS 122-62-3) are available. The key study was conducted according to OECD 301B under aerobic conditions using non-adapted activated sludge, from a STP which predominately treats domestic sewage, as inoculum (Defleur, 1998). Based on CO2 evolution a degradation of 84.6% was observed after 28 days and the 10-day window was passed. Hence, the substance is determined to be readily biodegradable according to OECD criteria.

This is confirmed by a supporting study, which was conducted according to OECD guideline 301B under aerobic conditions using non-adapted activated sludge as inoculum (Mead & Sewell, 1994). A biodegradation of 65% within 28 days was observed; however, the 10-day window was not passed. As ready biodegradability tests may fail because of the stringent test conditions, consistent positive test results supersede negative test results. Hence, based on the results of the key study, the substance is determined to be readily biodegradable according to OECD criteria.