2-Hydroxypropyl-β-cyclodextrine ethers

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Type of information:

experimental study

Adequacy of study:

key study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1997

Report date:

1997

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 111 (Hydrolysis as a Function of pH)

Test material

Test material information

Constituent 1

Test material form:

solid: particulate/powder

Radiolabelling:

not specified

Results and discussion

Total recovery of test substance (in %)

Total recovery of test substance (in %) 1

% Recovery:

104

pH:

4

Temp.:

50 °C

Duration:

5 d

Total recovery of test substance (in %) 2

% Recovery:

100

pH:

7

Temp.:

50 °C

Duration:

5 d

Total recovery of test substance (in %) 3

% Recovery:

82.4

pH:

9

Temp.:

50 °C

Duration:

5 d

Applicant's summary and conclusion

Validity criteria fulfilled:

yes