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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Parent compound pivaloyl chloride (CAS 3282-30-2): No data available.

Hydrolysis product pivalic acid (CAS 75-98-9): with high probability acutely not harmful to algae.

Hydrolysis product HCl (CAS 7647-01-0): Acutely very toxic for aquatic algae (pH dependent).

 

Key value for chemical safety assessment

EC50 for freshwater algae:
979 mg/L
EC10 or NOEC for freshwater algae:
246 mg/L

Additional information

No data are available for the parent compound pivaloyl chloride (CAS 3282-30-2). However, the parent compound rapidly hydrolyses in contact with water and forms pivalic acid (CAS 75-98-9) and HCl (CAS 7647-01-0). Therefore, the toxicity to aquatic green algae and cyanobacteria will be assessed based on the information available for the hydrolysis products pivalic acid and HCl.

 

Parent compound pivaloyl chloride:

No data available.

 

Hydrolysis product pivalic acid:

The toxicity of the hydrolysis product pivalic acid was tested in a GLP compliant study performed according to OECD 201 with Raphidocelis subcapitata (previous name Pseudokirchneriella subcapitata as test organism (Exxon, 2003). The 72-h ErC50 was found to be 979 mg/L. The NOEC is reported to be 246 mg/L. The test item concentration was analytically verified and effect values are therefore based on nominal test concentrations.

 

Hydrolysis product HCL:

The toxicity of the hydrolysis product HCl was tested in a GLP study according to OECD 201 with R. subcapitata (previous name P. subcapitata (MITI, 1999; peer reviewed data: OECD SIDS, 2002). The 72-h ErC50 was 0.492 mg/L (acid equivalent to pH 5.3). The NOEC was 0.097 mg/L (acid equivalent to pH 6).