Registration Dossier
Registration Dossier
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EC number: 221-921-6 | CAS number: 3282-30-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound pivaloyl chloride (CAS 3282-30-2): No data available
Hydrolysis product pivalic acid (CAS 75-98-9): with high probability acutely not harmful to aquatic invertebrates.
Hydrolysis product HCl (CAS 7647-01-0): Acutely very toxic for aquatic invertebrates (pH dependent).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- LC50
- Remarks:
- Pivalic acid
- Effect concentration:
- 202.9 mg/L
Additional information
No data for the parent compound pivaloyl chloride (CAS 3282-30-2) are available. However, the parent compound rapidly hydrolyses in contact with water and forms pivalic acid (CAS 75-98-9) and HCl (CAS 7647-01-0). Therefore, the acute toxicity to aquatic invertebrates will be assessed based on the information available for the hydrolysis products pivalic acid and HCl.
Parent compound pivaloyl chloride:
No data available.
Hydrolysis product pivalic acid:
The acute toxicity of the hydrolysis product pivalic acid to aquatic invertebrates was tested according to US EPA – 660/3-75-009 (Methods for Acute Toxicity with fish and Macroinvertebrates, and Amphibians; 1975) using Daphnia magna as test organism (EG & G Bionomics, 1977). The 48-h EC50 was found to be 202.9 mg/L, based on nominal test concentrations.
Hydrolysis product HCL:
HCl was tested in an acute toxicity test according to OECD 202 with D. magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; MITI, 1999; peer reviewed data: OECD SIDS, 2002).
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