Registration Dossier
Registration Dossier
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EC number: 202-678-5 | CAS number: 98-53-3
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Validated QSAR model. Calculation for 4-tert-butylcyclohexanone. Its validity has been proven for the domain of application “neutral organics” which is relevant for the substance.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
- Principles of method if other than guideline:
- Calculation based on ECOSAR v1.00, Estimation Programs Interface Suite™ for Microsoft® Windows v 4.10. US EPA, United States Environmental Protection Agency, Washington, DC, USA.
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-tert-butylcyclohexanone
- EC Number:
- 202-678-5
- EC Name:
- 4-tert-butylcyclohexanone
- Cas Number:
- 98-53-3
- Molecular formula:
- C10H18O
- IUPAC Name:
- 4-tert-butylcyclohexan-1-one
- Details on test material:
- - Name of test material (as cited in study report): 4-tert-butylcyclohexanone
- Molecular formula: C10H18O
- Molecular weight: 154.3 g/mole
- Smiles notation: C1CC(=O)CCC1C(C)(C)C
- Analytical purity: not applicable
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia sp.
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 12.234 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Any other information on results incl. tables
For detailed description on the model and its applicability, see 'Any other information on materials and methods incl. tables'.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
