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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer reviewed data; Advisory Committee on Existing Chemicals of Environmental Relevance (BUA) authorized by the Federal Ministry of the Environment, Nature Conservation and Nuclear Safety

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
2002

Materials and methods

Test guideline
Guideline:
other: growth inhibition test
Principles of method if other than guideline:
Growth Inhibitation Test according to Unger and Chiang
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chloro-2-nitroaniline
EC Number:
201-925-4
Cas Number:
89-63-4
Molecular formula:
C6H5ClN2O2
IUPAC Name:
4-chloro-2-nitroaniline

Test organisms

Test organisms (species):
Escherichia coli

Study design

Total exposure duration:
24 h

Results and discussion

Effect concentrations
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
34 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
Validity 2
Conclusions:
EC50 value of 34 mg/l was determined for a 24h exposure period