Registration Dossier
Registration Dossier
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EC number: 204-463-1 | CAS number: 121-30-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 121-30-2
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- Multicase model is used to estimate EC50 (growth) of algae.
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-amino-6-chlorobenzene-1,3-disulphonamide
- EC Number:
- 204-463-1
- EC Name:
- 4-amino-6-chlorobenzene-1,3-disulphonamide
- Cas Number:
- 121-30-2
- Molecular formula:
- C6H8ClN3O4S2
- IUPAC Name:
- 4-amino-6-chlorobenzene-1,3-disulfonamide
- Details on test material:
- - Name of test material: 4-amino-6-chlorobenzene-1,3-disulphonamide
- Molecular formula: C6H8ClN3O4S2
- Molecular weight: 285.73
- Substance type: Organic
- Physical state: Solid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- not specified
- Water media type:
- not specified
Results and discussion
Effect concentrations
- Dose descriptor:
- EC50
- Effect conc.:
- 120.25 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Remarks on result:
- other: duration not mentioned
Applicant's summary and conclusion
- Conclusions:
- Toxicity value of 4-amino-6-chlorobenzene-1,3-disulphonamide to Algae (Selenastrum capricornutum) is estimated to be EC50: 120.2502 mg/l.
- Executive summary:
Toxicity value of 4-amino-6-chlorobenzene-1,3-disulphonamide to Algae (Selenastrum capricornutum) is estimated to be EC50: 120.2502 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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