Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 200-002-3 | CAS number: 50-01-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
4.1 Appearance/physical state/colour
Guanidine hydrochloride is a solid, white, odourless organic substance.
4.2 Melting point/freezing point
The melting point of Guanidine hydrochloride is 188 °C
4.3 Boiling point
Decomposition of Guanidine hydrochloride above 231 °C
4.4 Density
The density of guaninie hydrochloride is reported to be 1.345 g/cm3
4.5 Particle size distribution (Granulometry)
Particle size distribution of Guanidine hydrochloride has a 50percentil of 139micrometer.
4.6 Vapour pressure
Waiving
4.7 Partition coefficient
Guanidine hydrochloride showed a log Kow < -1.70
4.8 Water solubility
The solubility of guanidinium chloride in water is reported to be 2150 g/l at 20 °C
4.9 Solubility in organic solvents / fat solubility
no study available
4.10 Surface tension
Waiving
4.11 Flash point
Waiving
4.12 Auto flammability
Guanidine hydrochloride shows no self ignition at heating up to the melting point (183 °C)
4.13 Flammability
Guanidine hydrochloride does not burn when in contact with a heated platinum wire
4.14 Explosiveness
waiving
4.15 Oxidising properties
waiviing
4.16 Oxidation reduction potential
no study available
4.17 Stability in organic solvents and identity of relevant degradation products
waiving
4.18 Storage stability and reactivity towards container material
no study available
4.19 Stability: thermal, sunlight, metals
no study available
4.20 pH
no study available
4.21 Dissociation constant
Salt of a strong acid with a strong basic.
4.22 Viscosity
waiving
4.23 Additional physico-chemical information
no study available
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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