Registration Dossier

Administrative data

Description of key information

Recent guideline studies are available on skin and eye irritation. According to the study results, gallium arsenide is not irritating to the skin or to eyes. 
NTP studies (NTP, 2000) with rats and mice revealed that after repeated inhalation exposure to a fine dust of GaAs a pulmonary alveolar proteinosis occurs leading to a pulmonary chronic inflammation .

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

From the present studies with sufficient reliability the toxicological profile of GaAs can be described as follows:


GaAs is not irritating to skin or to the eyes.



Effects on respiratory irritation: irritating

Justification for classification or non-classification

Recent guideline studies are available on skin and eye irritation. According to the study results, gallium arsenide is not irritating to the skin or to eyes and is thus not classified as irritant according to the criteria of the CLP-regulation (EC) No. 1272/2008 or the criteria by Directive 67/548/EEC.