Registration Dossier
Registration Dossier
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EC number: 215-114-8 | CAS number: 1303-00-0
Endpoint summary
Administrative data
Description of key information
There are 2 key studies with sufficient reliability: one with oral administration and one with dermal application.
Further 2 studies with oral administration and 6 studies with administration of GaAs by other routes have no sufficient reliability and are therefore ignored.
A single dosage of 10000 mg GaAs/kg bw either administered orally or applied dermally had no effect.
According to the results of these 2 studies GaAs can be classified as practically nontoxic and a classification for acute toxicity is not required.
Key value for chemical safety assessment
Additional information
A single dosage of 10000 mg GaAs/kg bw either administered orally or applied dermally has no effect. This is in good agreement with the properties of GaAs as they were seen in the water solubility study: GaAs is practically not soluble in water. Dissolution of GaAs in water only occurs as the result of oxidation. This seems to be a relatively slow process not relevant during single oral administration or application of GaAs to the skin.
Justification for classification or non-classification
A single dosage of 10000 mg GaAs/kg bw either administered orally or applied dermally has no effect.
GaAs can be classified as practically nontoxic and a classification for acute toxicity is not required according to the criteria of the CLP-regulation.
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