Registration Dossier

Administrative data

Endpoint:
biochemical or cellular interactions
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: special in-vitro investigation; Documentation regarding DMBA is very limited

Data source

Reference
Reference Type:
publication
Title:
Cytoplasmic vacuolation of mouse peritoneal macrpohages and uptake into lysosomes of weakly basic substances|J.
Author:
Okuma S, Poole B
Year:
1981
Bibliographic source:
Cell Biology 90: 656-664

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzyldimethylamine
EC Number:
203-149-1
EC Name:
Benzyldimethylamine
Cas Number:
103-83-3
Molecular formula:
C9H13N
IUPAC Name:
benzyldimethylamine

Results and discussion

Any other information on results incl. tables

RS-Freetext:
Dimethyl-benzyl-amine causes large lysosomal vacuoles in mouse peritoneal macrophages in vitro.

Applicant's summary and conclusion