Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Hydrolysis

The abiotic degradation of the test item 4-Hydroxy TEMPO was conducted according to OECD TG 111, Regulation (EC) No 440/2008, method C.7., and in accordance with OPPTS 835.2110. A sufficient number of measurements were made to estimate if less than 10% of hydrolysis is observed after five days at 50°C. In the preliminary test at 50°C the test item was stable at pH 4, 7 and 9 due to the fact that the observed hydrolysis was less than 10% after five days (120 h) at the test temperature of 50 ± 0.5°C. Therefore no further testing was necessary. According to the guideline, a half-life period at 25°C of more than one year may be estimated.

Biodegradation:

The biotic degradation potential of 4-Hydroxy TEMPO was investigated according to EU-method C.4-A. After 28 days incubation the test item reached 9 % degradation. Therefore 4-Hydroxy-TEMPO cannot be considered ready biodegradable.

Bioaccumulation:

The bioaccumulation potential of 4-Hydroxy TEMPO was estimated by calculation of the BFC with EPIWIN software using BCFBAF v1.5. A BCF value of 3.162 L/kg wwt and a log Kow of 0.55 were calculated. Thus 4-Hydroxy-TEMPO can be considered that it is unlikely to have potential for bioaccumulation.

Adsorption/desorption:

The adsorption / desorption of 4-Hydroxy TEMPO was estimated by calculation of the log Koc with EPIWIN software using KOCWIN. A log Koc value of 0.7743 and a log Kow of 0.55 were calculated. Thus the test item can be considered that it is unlikely to have potential for adsorption / desorption.