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Diss Factsheets
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EC number: 218-760-9 | CAS number: 2226-96-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Stability: thermal, sunlight, metals
Administrative data
Link to relevant study record(s)
- Endpoint:
- thermal stability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-07-06 to 2012-08-15
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study is regarded as reliable without restrictions because it was conducted in compliance with GLP regulation and guideline.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 113 (Screening Test for Thermal Stability and Stability in Air)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Test substance thermally stable:
- yes
- Operating temp.:
- >= 30 - <= 68 °C
- Remarks on result:
- other: All test showed an endothermic event (melting) with an mean onset temperature of 68 °C and an exothermal event (decomposition) starting at 150 °C and lasting over a wide temperature range up to approximately 300 °C.
- Sublimation:
- no
- Test substance stable to sunlight:
- not determined
- Test substance stable to metals / metal ions:
- not determined
- Conclusions:
- The test item is classified to be thermally stable at room temperature.
Reference
In the table below the recorded data of all measurements are summarized.
Event No. |
Heat flow |
Exothermic events |
Test 1 |
Test 2 |
Test 3 |
1 |
endothermal |
Onset [°C] |
68.3 |
68.4 |
66.1 |
2 |
exothermal |
Onset [°C] |
150 |
150 |
150 |
Peak Maximum [°C] |
212 |
213.6 |
211 |
||
Int. norm. [J/g] |
810 |
409 |
715.5 |
||
|
|
Loss in weight [mg] |
0.0 |
15.7 |
0.0 |
|
|
Loss in weight [%] |
0 |
85 |
0 |
All test showed an endothermic event (melting) with an mean onset temperature of 68 °C and an exothermal event (decomposition) starting at 150 °C and lasting over a wide temperature range up to approximately 300 °C. Experiment 2 was performed with an open crucible at ambient atmosphere. At this test a significant loss of mass was found.
Description of key information
In a thermal stability study, no exothermal event was observed below the decomposition temperature. Therefore the test item 4-Hydroxy TEMPO is classified to be thermally stable at room temperature.
Additional information
The thermal stability of 4-Hydroxy TEMPO was determined according to the OECD TG 113. Samples of the test item were weighed into glass crucibles. All samples were exposed to a temperature/time-gradient while the thermal heat-flow was recorded. All tests showed an endothermic event (melting) with an mean onset temperature of 68 °C and an exothermal event (decomposition) starting at 150 °C and lasting over a wide temperature range up to approximately 300 °C. According to the OECD Guideline 113 an exothermic event is assumed to be a decomposition. None of the results showed an exothermal event starting below 150 °C. Therefore the test item 4-Hydroxy TEMPO is classified to be thermally stable at room temperature.
Justification for classification or non-classification
Based on the study results, the substance was considered to be thermally stable at room temperature. No classification with regard to thermal stability according to Directive 67/548/EEC (DSD) and Regulation (EC) No 1272/2008 (CLP) is required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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