Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 221-435-4 | CAS number: 3091-25-6
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
All studies were considered as key as they cover different endpoints under REACH. All of the three studies were reliable guideline studies which could be used alone to address these end points and were all assigned a Klimisch score of 1.
Short description of key information:
Genetic toxicity in vitro, 001: Negative for a bacterial reverse mutation assay.
Genetic toxicity in vitro, 002: Negative for a mammalian cell gene mutation assay.
Genetic toxicity in vivo, 001: Negative for a micronucleus assay addressing the chromosome aberration endpoint.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
As all of the studies were negative, no classification of trichlorooctylstannane would be required with respect to genetic toxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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