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Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Well documented study according OECD 107 and GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
GLP compliance:
yes (incl. certificate)
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report):Benzenesulphonyl chloride (Provichem 0203)
-Molecular weight: 176.62
- Analytical purity: 99.95%
- Production date: 04/11/2009
- Lot/batch No.: 200911040020
-Shelf-life: 1 year
-Date of receipt: 05/02/2010
- Storage condition of test material: ambient room temperature 20-30°C
- Other:

Study design

Analytical method:
gas chromatography

Results and discussion

Partition coefficientopen allclose all
Type:
log Pow
Partition coefficient:
3.39
Temp.:
23 °C
Remarks on result:
other: log Kow
Type:
Pow
Partition coefficient:
2 588
Temp.:
23 °C
Remarks on result:
other: Kow
Details on results:
The ratio of n Octanol:water used in the study was 1:1, 1:2, and 2:1 resulted in partition coefficient (Kow) values of 102.26, 99.69, and 105.24 and log partition coefficients (log10 Kow) values of 2.01, 2.00, and 2.02 respectively.

Any other information on results incl. tables

The ratio of n Octanol:water used in the study was 1:1, 1:2, and 2:1 resulted in partition coefficient (Kow) values of 2242, 1832, and 3690 and log partition coefficients (log10 Kow) values of 3.35, 3.26, and 3.57 respectively. The mean partition coefficient (Kow) was 2588 and the log partition coefficient (log10 Kow) of Benzenesulphonyl chloride (Provichem 0203) was 3.39 ± 0.14 at 23+2°C.

Applicant's summary and conclusion

Conclusions:
Partition coefficient of Benzenesulphonyl chloride (Provichem 0203) was determined in water. The ratio of n Octanol:water used in the study was 1:1, 1:2, and 2:1. Benzenesulphonyl chloride (Provichem 0203) was determined to have a mean Kow of 2588 and log10 Kow of 3.39 + 0.14 at 23+2°C.