Registration Dossier

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The effect of 6-tert-butyl-m-cresol and other substituted phenols on liver weights and liver enzymes (hexabarbitone oxidase and aminopyrine demethylase) was determined in the rat. A significant increase in liver weight but no significant induction of liver enzymes was observed.

Additional information

in the case of 6 -tert-butyl-m-cresol no significant relationship between liver weight increase and enzyme induction was observed