Registration Dossier
Registration Dossier
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EC number: 217-568-2 | CAS number: 1889-67-4
Endpoint summary
Administrative data
Description of key information
Additional information
Stability
The performance of a hydrolysis as a function of pH test is scientifically not justified as the test item is practically insoluble in water.
Biodegradation
Biodegradation in water: screening tests
1,1'-(1,1,2,2-tetramethylethylene)dibenzene was assessed in a closed bottle test in accordance with OECD guideline 301 D and EU method C.4 VI. The test item was exposed to activated sludge from an aeration tank for 28 days. Under the test conditions the percentage biodegradation of the material reached a mean of 0.2 % based on ThODNH4. Thus, the test item has to be considered as not ready biodegradable.
Simulation tests on biodegradation in soil as well as water and sediment have been requested in a CCH decision and work on these studies is currently ongoing. The dossier will be updated with the new information by the set deadline in the final decision.
Bioaccumulation
A study according to OECD 305 has been requested in decision CCH-D-2114543301-63-01/F and is currently ongoing. The endpoint will be updated with the new information by the set deadline in the final decision. The bioaccumulation potential of the test item was estimated using QSAR models as a temporary solution for the risk assessment.
Using VEGA v1.1.4 model CAESAR v2.1.14 the BCF value of the test item was calculated to be 999 L/kg. Using T.E.S.T. v4.2.1 the BCF value of the test item was calculated to be 1275 L/kg. The substance is within the applicability domain of both model. Thus, the estimations are considered to be accurate. For risk assessment purposes as worst case scenario the value of 1275 L/kg was chosen as a key value.
Transport and distribution
The adsorption coefficient (Koc) on soil and sewage sludge of 1,1'-(1,1,2,2-tetramethylethylene)dibenzene was assessed according to EU method C.19 and OECD guideline no. 121 using the HPLC method. Based on the retention time measured for 1,1'-(1,1,2,2-tetramethylethylene)dibenzene (8.25 min), the log Koc was estimated to be 4.20 ± 0.007 (95 % confidence interval) corresponding to a Koc of 15968 ± 254.8 (95 % confidence interval) at 25 °C.
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