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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The acute toxicity of 1-chloro-2-methylbenzene towards fish was tested following the OECD Guideline 203 yielding a LC50(96 h) of 7.7 mg/L (NITE 2000).

Key value for chemical safety assessment

LC50 for freshwater fish:
7.7 mg/L

Additional information

1 -Chloro-2 -methylbenzene has to be scored as volatile. Therefore, an information concerning analytical monitoring during biological assays would be quite crucial. Despite there is no information available whether concentrations were analytically confirmed the study was chosen as key study as the source is scored as reliable according to the Guidance Document R.7b (ECHA, 2008).

The results of acute aquatic bioassays are used in the scope of classification and labelling. Summarizing the acute effects of the test item toward aquatic organisms, daphnids are the most sensitive species having a EC50(48 h) of 0.7 mg/L, resulting in a classification as very toxic towards aquatic life (R50). As this is the most stringent classification, an additional fish test would not provide new evidence to assess the hazard of the test item towards aquatic life.

The Federal Register (USA 1982) reported the most sensitive 96-hour LC50 value of 2.3 mg/L on Oncorhynchus mykiss. As this study is not yet available, its reliability cannot be assessed. Nevertheless, that value assumes effects in the same concentration range as the value presented by NITE (2000).