Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-652-6 | CAS number: 109-16-0
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- Human and rat|mononuclear cell proliferation show different sensitivity, in vitro, to single constituents of dental composite resins.
- Author:
- Aronsson G, Dahlgren UI, Karlsson S
- Year:
- 2 000
- Bibliographic source:
- J. Biomed. Mater. Res. 53(6): 651 - 657
Materials and methods
- Type of study / information:
- Type: Cell proliferation in vitro
Test material
- Reference substance name:
- 2,2'-ethylenedioxydiethyl dimethacrylate
- EC Number:
- 203-652-6
- EC Name:
- 2,2'-ethylenedioxydiethyl dimethacrylate
- Cas Number:
- 109-16-0
- Molecular formula:
- C14H22O6
- IUPAC Name:
- ethane-1,2-diylbis(oxyethane-2,1-diyl) bis(2-methylacrylate)
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- Purity: no data
Results and discussion
Any other information on results incl. tables
Results:
ID50: 5 umol/L
The concentration at which the proliferation rate was
reduced by 50% (ID50-value), was graphhhhhically obtained
from individual dose vs. response curves. As the counts per
min (cpm) varied ammong experiments, the graphs were
constructed with data expressed as percent of the control
containing 0.1 % ethanol (control = 100 %). The inhibition rank order
is based on the median value of the ID50 values for each
substance.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
