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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

1,4-BDDMA is readily biodegradable and fulfils the 10-d window criterion (OECD Guideline 310; Headspace Test and OECD Guideline 301 B; CO2 evolution test).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

One study on biodegradation of 1,4-BDDMA as well as one study on biodegradation of the structural analogue 1,3-BDDMA are available, which are both considered as reliable without restrictions (Klimisch score 1):

The ready biodegradation of 1,4-BDDMA was investigated in a study conducted according to OECD Guideline 310 (Headspace Test), adopted 23 March 2006, over a period of 28 days and using predominantly domestic non-adapted activated sludge as inoculum. The biodegradation rate was determined by measurement of CO2 evolution. Inoculum blank, toxicity control and procedural/functional control with the reference substance sodium benzoate were performed.The functional control reached the pass level of 60% after 3 days. 

The 10% level (beginning of biodegradation) was reached after 2 days. The pass level of 60% was reached after 9 days and the biodegradation came to 84 % after 28 days. The 95% confidence interval on day 28 was 76 - 92% 

The biodegradation of the toxicity control reached 83% within 14 days and 89% after 28 days. The biodegradation of the reference item was not inhibited by the test item in the toxicity control.The 95% confidence interval on day 28 was 86 - 93%

1,4-BDDMA was readily biodegradable fulfilling the 10-d window criterion.

 

In a supporting study the structural analogue 1,3-BDDMA has been tested for biodegradation: 

The ready biodegradation of 1,3-BDDMA was investigated in a study conducted according to OECD Guideline 301 B (CO2 evolution test), adopted 17th July 1992, and EU Method C.4-C, 31 July 1992, over a period of 28 days and using domestic sewage as inoculum. The biodegradation rate was determined by measurement of CO2 evolution. Inoculum blank and procedural/functional control with the reference substance sodium acetate were performed.

The functional control reached the pass level >60% after 14 d (68.5%).

The 10-day window started on day 6. Biodegradation totalled 57% at the end of the 10 day window (day 16) and 74% at the end of the test period.

A degradation of 60% has to be reached in a 10-day window within 28 days in order to classify the test substance as readily biodegradable. Based on this criterion, 1,3-BDDMA is not readily biodegradable. But as the pass level is almost fulfilled (degradation slightly below 60%), the test substance can be considered as inherently biodegradable.