Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 404-310-0 | CAS number: 10591-85-2 PERKACIT TBZTD; PERKACIT TBZTD PDR; PERKACIT TBZTD PDR-D; TBZD
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Guideline study performed in compliance with GLP, available as unpublished report, no restrictions, fully adequate for assessment.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): Tetrabenzylthiuram disulfide
- Substance type: Monoconstituent substance
- Physical state: Solid
- Storage condition of test material: At room temperature in the dark
- Lot/batch No.: RB82 + RB87 + RB88 + RB92 + RB69 - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- ca. 3.7
- Temp.:
- 20 °C
- Remarks on result:
- other: Second log Pow = 3.4 relates probably to a decomposition product
- Conclusions:
- The determination of log Pow by High Performance Liquid Chromatography (HPLC) results in two log Pow
- Executive summary:
The log Pow of the substance was interpolated from this regression line which was obtained from nine reference substances. Two partition coefficients (noctanol/water) were associated with the test substance and determined to be 2.5 * 10E3 (log Pow = 3.4) and 5.0 * 10E3 (log Pow = 3.7) at 20.0 ± 0.50 C. The lower value represents probably a decomposition product, the higher the test substance.
Reference
Description of key information
The test substance is not stable in water. With a High Performance Liquid Chromatographic method two partition coefficients (n-octanol/water) were determined to be 2.5* 10E3 (log P = 3.4) and 5.0 * 10E3 (log P =3.7) at 20.0 ± 0.50 C.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.7
- at the temperature of:
- 20 °C
Additional information
The pattern of a chromatogram of the test substance showed two different peaks, probably one derived from the test substance and one from decomposition product(s). The higher of the two log P values was associated with the original substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
