Registration Dossier
Registration Dossier
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EC number: 295-394-6 | CAS number: 92045-12-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Read across justification
Several criteria justify the use of the read across approach to fill data gaps for foots oils using other lubricant base oil analogs. Primarily the basis for the read-across is the similar physical chemical properties shared by the foots oils and other lubricant base oils.
Short-term toxicity to aquatic algae and cyanobacteria has been filled by read-across of measured data from other lubricant base oils. It is supported in a weight of evidence approach by a calculated value using composition information derived from two dimensional gas chromatography in conjunction with the PETROTOX model.
In a read-across key static 72-hour algal (Pseudokirchneriella subcapitata) limit test (OECD 201; KS = 2), the freshwater alga was exposed to the Water Accommodated Fraction (WAF) of an other lubricant base oil (N100DW), at a nominal concentration of 100 mg/L. The NOEL was ≥ 100 mg/L based upon average specific growth rate and cell yield (Petro-Canada, 2008).
Supporting data estimated from the PETROTOX computer model show no acute toxicity of foots oil to algae at or below its maximum attainable water solubility (Redman et al., 2010b). These data support the applied read across.
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