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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Basic toxicokinetics

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Administrative data

Endpoint:
basic toxicokinetics
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: peer-reviewed reports from EPA and OECD

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
HUMAN HEALTH AND ECOLOGICAL HAZARDS SUMMARY
Author:
United States Environmental Protection Agency (US EPA)
Bibliographic source:
HUMAN HEALTH AND ECOLOGICAL HAZARDS SUMMARY
Reference Type:
secondary source
Title:
SIDS Dossier Potassium Sulfate
Author:
OECD
Year:
2007
Bibliographic source:
OECD HPV Chemical Programme, SIDS Dossier, approved at SIAM 25 (16-19 October, 2007)
Report date:
2007

Materials and methods

Test guideline
Qualifier:
no guideline available
Deviations:
not specified
Principles of method if other than guideline:
no data available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Potassium sulfate
EC Number:
231-915-5
EC Name:
Potassium sulfate
Cas Number:
7778-80-5
Molecular formula:
H2O4S.2K
IUPAC Name:
dipotassium sulfate

Results and discussion

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): no bioaccumulation potential based on study resultsAbsorption of potassium sulfate is expected to be nil through the skin and good through the lungs and GI tract. No significant adverse effects from potassium sulfate representing parts of the ionic inorganic components of aluminium potassium bis sulphate are to be expected. After absorption and distribution potassium and sulfate should be complete excreted through urine and feces.The read across substance potassium sulfate is an inorganic salt with high aqueous solubilityand will exist in a dissociated form in solution and, thus will not bioaccumulate. .Therefore potassium sulfate representing parts of ionic inorganic components of aluminium potassium bis sulphate should have no relevant bioaccumulation potential.
Executive summary:

Absorption of potassium sulfate is expected to be nil through the skin and good through the lungs and GI tract.

No significant adverse effects from potassium sulfate representing parts of the inorganic components

of aluminium potassium bis sulphate are to be expected.

After absorption and distribution potassium and sulfate should be complete excreted through urine and feces.

Therefore potassium sulfate representing parts of ionic inorganic components of aluminium potassium bis sulphate

should have no relevant bioaccumulation potential.