Wastewater, cadmium sulfate electrolytic, acid

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

migrated information: read-across based on grouping of substances (category approach)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Acceptable, well documented publicationthat meets basic scientific principle but no standard test

Data source

Reference

Reference Type:

publication

Title:

Cadmium toxicity and accumulation in eggs and alevins of Atlantic salmon Salmo salar

Author:

Rombough & garside

Year:

1982

Bibliographic source:

Can. J. Zool. 60(8): 2006-2014

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

24d mortality test on juveniles

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Cadmium chloride

EC Number:

233-296-7

EC Name:

Cadmium chloride

Cas Number:

10108-64-2

IUPAC Name:

cadmium dichloride

Details on test material:

none

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Details on test solutions:

Municipal water charcoal filtered and UV sterilised.

Test organisms

Test organisms (species):

Salmo salar

Details on test organisms:

TEST ORGANISM
- Common name: Atlantic salmon
- Source: newly hatched alevins from fish culture station
- habitat concentration 1-14 µg/L

Study design

Test type:

semi-static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

24 d

Test conditions

Hardness:

19-28 mg CaCO3/l

Test temperature:

5-10 °C

pH:

6.5 to7.3

Dissolved oxygen:

11.1 to 12.5 mg O2/l

Salinity:

N/A

Nominal and measured concentrations:

control - 0.32 - 1 - 3.2 - 10 - 32 - 100 - 320 - 1000 - 3200 - 10000 - 320000 µg Cd/L

Details on test conditions:

Alcalinity 14-17 mg CaCO3/L
Background concentration = 0.13 µg Cd/L

Reference substance (positive control):

no

Results and discussion

Effect concentrations

Duration:

24 d

Dose descriptor:

LC50

Effect conc.:

34 µg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

dissolved

Basis for effect:

mortality (fish)

Reported statistics and error estimates:

Alevin survival data were analysed with Biomedical survivorship program (BMD 01S)

Any other information on results incl. tables

Sublethal observations / clinical signs:

none

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Conclusions:

Test is not done according to standard protocol but is of good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. The study was used for that purpose in the EU risk assessment process on cadmium (ECB 2008).

Executive summary:

Tests not done according to standard protocol, but of good quality and considered useful for setting the reference value for acute aquatic ecotoxicity. Study used for that purpose in the EU risk assessment process on cadmium (ECB 2008). Culture medium, test water conditions well described and relevant the purpose of classification.