3-aminopropan-1-ol

Additional toxicological data

Administrative data

Endpoint:

additional toxicological information

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference Type:

publication

Title:

Cytotoxicity of Amino Alcohols to Rat Hepatoma-derived Fa32 Cells

Author:

Scheers EM, Forsby A, Dierickx PJ

Year:

2002

Bibliographic source:

ATLA 30: 309-312 ( Nineteenth Scandinavian Cell Toxicology Congress)

Materials and methods

Type of study / information:

Cytotoxicity of rat hepatoma-derived Fa32 cells

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

Cytotoxicity was measured by using a NRU (neutral red uptake) inhibition assay and was quantified by determination of the NI50, i.e. the concentration of test compound needed to induce a 50% reduction in NRU.

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

3-aminopropan-1-ol

EC Number:

205-864-4

Cas Number:

156-87-6

Molecular formula:

C3H9NO

IUPAC Name:

3-aminopropan-1-ol

Test material form:

liquid

Results and discussion

Any other information on results incl. tables

The NI₅₀of 3-aminopropan-1 -ol was 13.4 ± 2.3 mM.