Registration Dossier
Registration Dossier
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EC number: 205-864-4 | CAS number: 156-87-6
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Cytotoxicity of Amino Alcohols to Rat Hepatoma-derived Fa32 Cells
- Author:
- Scheers EM, Forsby A, Dierickx PJ
- Year:
- 2 002
- Bibliographic source:
- ATLA 30: 309-312 ( Nineteenth Scandinavian Cell Toxicology Congress)
Materials and methods
- Type of study / information:
- Cytotoxicity of rat hepatoma-derived Fa32 cells
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Cytotoxicity was measured by using a NRU (neutral red uptake) inhibition assay and was quantified by determination of the NI50, i.e. the concentration of test compound needed to induce a 50% reduction in NRU.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-aminopropan-1-ol
- EC Number:
- 205-864-4
- Cas Number:
- 156-87-6
- Molecular formula:
- C3H9NO
- IUPAC Name:
- 3-aminopropan-1-ol
- Test material form:
- liquid
Constituent 1
Results and discussion
Any other information on results incl. tables
The NI50of 3-aminopropan-1 -ol was 13.4 ± 2.3 mM.
Applicant's summary and conclusion
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