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Dissociation constant

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The dissociation constant of the test substance is waived due to the low solubility of the test substance in water. The solubility is < 20 ppb. All three methods described in the OECD Guideline require solubility greater than this in order for detectable measurements to be made. The three methods are based on titration, UV/Vis spectroscopy, and conductivity.

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