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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 204-464-7 | CAS number: 121-32-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- Little information about the test conditions but authors refers to OECD guidelines and temperature is stated
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- flask method
- Key result
- Water solubility:
- 2 820 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: No information on pH
- Details on results:
- In the publication authors give Log Sw value (Log Sw= -1.77 mol/L).
Sw has been deduced as follow : Sw = (inv [Log -1.77 ])*MW
With MW = 166.175 g/mol - Conclusions:
- Interpretation of results: the test item is soluble (1000-10000 mg/L)
Ethylvanillin has a water solubility of 2820 mg/L at 25°C. - Executive summary:
In a study (Jin et al., 1998), the water solubility of ethylvanillin was measuresd using the flask method.
The measured water solubility was 2820 mg/L.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- No test substance information, no guideline, secondary literature, but reference database.
- Guideline:
- other: no data
- GLP compliance:
- not specified
- Key result
- Water solubility:
- 2 860 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: No data on pH
- Conclusions:
- Interpretation of results: the test item is soluble (1000-10000 mg/L)
Ethylvanillin has a water solubility of 2860 mg/L at 25°C (reference database). - Executive summary:
Ethylvanillin has a water solubility of 2860 mg/L at 25°C.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- No test substance information, no guideline, secondary literature, but reference database.
- Guideline:
- other: no data
- GLP compliance:
- not specified
- Key result
- Water solubility:
- 4 g/L
- Remarks on result:
- other: No data on pH and T°C
- Conclusions:
- Interpretation of results: the test item is soluble (1000-10000 mg/L)
Ethylvanillin has a water solubility of 4000 mg/L. - Executive summary:
Ethylvanillin has a water solubility of 4000 mg/L (reference database).
Referenceopen allclose all
No more data on results.
No more details.
No more details.
Description of key information
Water solubility: 2820 mg/L at 25°C to 4000 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 2 820 mg/L
- at the temperature of:
- 25 °C
Additional information
Different values from Handbook or literature are available. As they are in the same range, no key study is selected and a "weight of evidence approach" was applied.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.