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EC number: 421-820-9
CAS number: 192268-65-8
CD 28-0132; IRGALUBE 232
The substance is considered to be very persistent in the environment
Based on biodegradation screening and simulation tests, the substance is
considered to be persistent in the environment. The substance to
register was found to be poorly biodegradable in a Closed bottle test
according to OECD guideline 301D (Huntington 1996). In addition, several
biodegradation data are available for the main component Triphenyl
thiophosphate (structure A). 17.8 and 19.3% mineralization (CO2
evolution) was observed in 28 days in a modified Sturm test (OECD 301B).
Further investigations during experimental phase using radiolabelled
test item showed that only 51.5% and 60.8% of the radioactivity
consisted of the test item, whereas the remaining radioactivity
consisted of its degradation products. Thus, the test item is not
completely biodegraded over a 28-day period under the test conditions
but up to 19% is mineralized and additionally up to 48.5% of the test
item is transformed into its transformation and degradation products.
Phenol can be identified from the chromatogram of the degradation
products. This is supported by the results of the hydrolysis study,
which showed that different transformation products of the test
substances are generated in parallel once hydrolysis has started. The
results indicate that the test item cannot be classified readily
biodegradable but well primarily degradable under conditions of the
test. An inherent biodegradability test with Structure A according to
OECD 302C confirmed this result. The test material showed up to 59.5 and
66.8 % biodegradation after 28 days. These results indicate that the
test item can be degraded if sufficient degrading microorganisms are
available; however, this is not necessarily be the case in surface
water. A study investigating the biodegradation of O,O,O-triphenyl
phosphorothioate under environmental conditions according to GLP and
OECD guideline 309 using radiolabelled test material showed only very
low mineralization of 3.1 – 3.7%. No organic volatiles were detected (≤
0.1 % AR). The amount of parent after 61 days was in the range of 80.2 %
to 90.5 % AR. The DT50 value is determined to be > 61 days. Reason for
the low degradation are assumed to be low microorganism concentrations
and adsorption of the components to DOC which might lower
bioavailability of the substances to microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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