Registration Dossier
Registration Dossier
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EC number: 271-235-6 | CAS number: 68526-86-3
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The following is taken into account for any hazard/risk/persistency assessment:
Aliphatic alcohols are resistant to hydrolysis because they lack a functional group that is hydrolytically reactive. Therefore, this fate process will not contribute to a measurable degradative loss of this substance from the environment
Key value for chemical safety assessment
Additional information
Hydrolysis
of an organic molecule occurs when a molecule (R-X) reacts with water
(H2O) to form a new carbon-oxygen bond after the carbon-X bond is
cleaved. Mechanistically,
this reaction is referred to as a nucleophilic substitution reaction,
where X is the leaving group being replaced by the incoming nucleophilic
oxygen from the water molecule.
Chemicals that are susceptible to hydrolysis contain functional groups
that can be displaced by a nucleophilic substitution reaction. Substances
that have the potential to hydrolyze include alkyl halides, amides,
carbamates, carboxylic acid esters and lactones, epoxides, phosphate
esters, and sulfonic acid esters. The
lack of a leaving group renders a compound resistant to hydrolysis.
Aliphatic alcohols are resistant to hydrolysis because they lack a
functional group that is hydrolytically reactive.Therefore, this
fate process will not contribute to a measurable degradative loss of
this substance from the environment.
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