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Short-term toxicity to fish

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Description of key information

The acute toxicity of of the structural analogue dipotassium hexafluorotitanate to Danio rerio (zebra fish) was tested according to OECD 203; an LC50 of 117.42 mg/L  was recalculated for dihydrogen hexafluorotitanate .

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
117.42 mg/L

Additional information

Dihydrogen hexafluorotitanate

The acute toxicity of the structural analogue dipotassium hexafluorotitanate to Danio rerio (zebra fish) was tested according to OECD 203. An LC50 of 117.42 mg/L was recalculated for dihydrogen hexafluorotitanate indicating a similar potential for acute toxicity to fish (or a lack thereof) as other fluoride substances (see below).

Potassium fluoride

LC50 values of 107.5, 92.4, 118.5, 105.1, 64.1 ppm at 96, 120, 144, 168 and 192 h respectively are reported for rainbow trout (Camargo & Tarazona, 1991). The same authors report LC50 value for brown trout of 164.5, 135.6, 118.5, 105.1 and 97.5 ppm after 96, 120, 144, 168 and 192 h respectively. The EU RAR for hydrogen fluoride reports additional LC50 values of 299 mg/L (48h in Leuciscus idus); 51 mg/L in (96h in Onchorynchus mykiss) and 340 mg/L (96h in Gasterosteus aculeatus). The RIVM Integrated Criteria Document reports additional data, with LC50 values ranging from 128 -460 mg/L (Sloof et al, 1988). The RIVM document also reports LC50 values of >100 mg/L (the limit of solubility) for sodium fluoride in seawater.

The key value for the risk assessment is considered to be an LC50 of 51 mg/L in Onchoryhnchus mykiss reported by Janssen (1989) in the appendix to the ICD report.