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Acute toxicity of hydroxypropyl acrylate was investigated on all three trophic levels.


LC50(96h) = 3.61 mg/L Pimephales promelas

LC50(96h) = > 10 -< 22 mg/L Leuciscus idus


EC50(48h) = 24 mg/L Daphnia magna


ErC50(72h) = 6.98 mg/L Pseudokirchnerella subcapitata

NOEC(72h) = 0.625 mg/L Pseudokirchnerella subcapitata

Thus, effect values were all in the same range of concentrations, i.e. between 1 and 10 mg/L, or higher.

This is supported by a solid data set from the structural analogue 2 -hydroxyethyl acrylate.


LC50(96h) = 4.8 mg/L Pimephales promelas

LC50(96h) = 6.5 mg/L Oryzias latipes

LC50(96h) = 6.81 mg/L Leuciscus idus

LC50(96h) = 17.5 mg/L Cyprinodon variegatus


EC50(48h) = 5.2 mg/L Daphnia magna


ErC50(72h) = 6.0 mg/L Pseudokirchnerella subcapitata

NOEC(72h) = 1 mg/L Pseudokirchnerella subcapitata

In addition, a long-term investigation on the reproduction of Daphnia magna with the structural analogue HEA showed a NOEC (21d) of 0.48 mg/L.

Several toxicity tests towards microorganisms showed effect concentrations well above 100 mg/L. Therefore, inhibition of biodegradation of activated sludge is not expected when the test substance is introduced in appropriate low concentrations.