Registration Dossier
Registration Dossier
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EC number: 201-853-3 | CAS number: 88-72-2
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- auto-ignition temperature (liquids)
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Analytical purity: not specified
- Auto-ignition temperature:
- 420 °C
- Remarks on result:
- other: Atmospheric pressure was not reported. The value is assumed to be measured under normal atmospheric conditions.
- Executive summary:
NIOSH, 2009
The auto-ignition temperature of 2-nitrotoluene is 420 °C. Atmospheric pressure was not reported. The value is assumed to be measured under normal atmospheric conditions.
- Endpoint:
- auto-ignition temperature (liquids)
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Analytical purity: not specified
- Auto-ignition temperature:
- 420 °C
- Remarks on result:
- other: Atmospheric pressure was not reported. The value is assumed to be measured under normal atmospheric conditions.
- Executive summary:
HSDB, 2009
The auto-ignition temperature of 2-nitrotoluene is 420 °C. Atmospheric pressure was not reported. The value is assumed to be measured under normal atmospheric conditions.
Referenceopen allclose all
Description of key information
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report the same auto-ignition temperature (420 °C), collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
HSDB, 2009
The auto-ignition temperature of 2-nitrotoluene is 420 °C. Atmospheric pressure was not reported. The value is assumed to be measured under normal atmospheric conditions.
NIOSH, 2009
The auto-ignition temperature of 2-nitrotoluene is 420 °C. Atmospheric pressure was not reported. The value is assumed to be measured under normal atmospheric conditions.
Key value for chemical safety assessment
- Autoflammability / Self-ignition temperature at 101 325 Pa:
- 420 °C
Additional information
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