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Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation
Remarks:
in vivo
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The scientific validity of the (Q)SAR model has been established in accordance with the OECD Principles for (Q)SAR Model Validation. This study is used to provide a weight of evidence for the hazard endpoint that is sufficient for the purpose of classification and labelling and/or risk assessment. An additional study on this endpoint is available.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Principles of method if other than guideline:
OECD Toolbox v3.1
Estimation by TIMES: Skin sensitization v. 16.19 with autoxidation
Toolbox prediction report is attached in IUCLID
GLP compliance:
not specified
Type of study:
other: QSAR

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
SMILES:C(O)(C(O)C(O)CO)CO

Results and discussion

Any other information on results incl. tables

Results by QSAR utilising Times within the OECD Toolbox were negative indicating that the substance is not sensitising.

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information negative Criteria used for interpretation of results: expert judgment
Conclusions:
This study and the conclusions which are drawn from it fulfil the quality criteria (validity, reliability, repeatability).

Results by QSAR utilising Times within the OECD Toolbox were negative indicating that the substance is not sensitising.
Executive summary:

Results by QSAR utilising Times within the OECD Toolbox were negative indicating that the substance is not sensitising. The target substance falls within applicability domain of the prediction. Supporting documentation is provided in the attached prediction report.