Xylitol

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Principles of method if other than guideline:

In laser diffraction, the particles are dispersed through the laser beam in the air stream. The light is scattered when it meets a particle and the diffraction pattern is measured by a detector. The method relies on the fact that diffraction angle is inversely proportional to particle size. Particle size distribution is calculated by using matrix equations. The method is applicable to crystalline and milled materials.

GLP compliance:

not specified

Type of method:

Laser scattering/diffraction

Type of particle tested:

primary particle

Type of distribution:

other: laser diffraction

Percentile:

D50

Mean:

>= 0.15 - <= 2.4 mm

Remarks on result:

other: standard deviation not reported

Remarks on result:

other: No data

Conclusions:

Xylitol particle size may range from 0.15 mm (max 7%) to 2.4 mm (0%).

Executive summary:

Xylitol is a sugar alcohol in crystalline form. Xylitol’s particle size can be determined by using laser diffraction. Xylitol particle size may range from 0.15 mm (max 7%) to 2.4 mm (0%).

Description of key information

Laser scattering/diffraction method

Additional information

Xylitol is a sugar alcohol in crystalline form. Xylitol particle size may range from 0.15 mm (max 7%) – 2.4 mm (0%) based on a study conducted for the determination of particle size using the laser diffraction method.