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Diss Factsheets
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EC number: 205-554-9 | CAS number: 142-72-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Acute oral toxicity: Key studies: Read-across from experimental data on the analogue substance Calcium Acetate. The oral LD50 for Magnesium Acetate for female rats is calculated to be 2422 mg/kg bw (test method according to OECD 401).
Acute inhalation toxicity: Key studies: Read-across from experimental data on the analogue substance Calcium Acetate. The (4h) LC50 in male/female rats for Magnesium Acetate is calculated to be greater than 5.04 mg/L air (test method equivalent to OECD 403).
Acute dermal toxicity: Key studies: Read-across from experimental data on the analogue Fumaric Acid. The LD 50 for Magnesium Acetate is calculated to be greater than 24530.58 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 422 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 5 040 mg/m³ air
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 24 530.58 mg/kg bw
Additional information
Acute oral toxicity:
Key studies:
Read-across approach from experimental results on the analogue substance Calcium Acetate: Test method was according to OECD 401.
The oral LD50 for Magnesium Acetate was 2422 mg/kg/bw (in female rats was calculated to be 1749.28 mg/kg bw, and LD50 for male rats was between 2844.94 and 4177.38 mg/kg bw).
Acute inhalation toxicity:
Key studies:
Read-across approach from experimental results on the analogue substance Calcium Acetate: Test method was similar to OECD 403.
The LC50 value for 4 hours exposition at rat (male and female) is higher than 5.6 mg/L. At this dose no mortality was observed as well as any change during the pathology observations realized at the end of the study at 14 days.
For Magnesium Acetate, the LC50 was calculated to be greater than 5.04 mg/L.
Acute dermal toxicity:
Key study:
Read-across approach from experimental results from a study similar to OECD 402 guideline on the analogue Fumaric Acid. The LD50 for Fumaric Acid is greater than 20000 mg/kg bw for rabbits.
Based on this experimental result and the molecular weights, the read-across approach is applied and the LD 50 for Magnesium Acetate is calculated to be greater than 24530.58 mg/kg bw.
Justification for classification or non-classification
Acute toxicity:
Oral: > 2000 mg/kg bw: non- classification
Dermal: LC50 > 2000 mg/kg bw: non- classification
Inhalation: LC50 > 5 mg/L: non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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