Registration Dossier

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-02-04 (experimental phase)
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to a relevant guideline without deviations. It was not carried out according to GLP, but it was performed in a test facility which has been certified to be in compliance with the principles of GLP.
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
from May 30, 2008
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
adopted July 27, 1995
Deviations:
no
GLP compliance:
no
Remarks:
However, the study was performed in a test facility which has been certified to be in compliance with the principles of GLP.
Type of method:
thermal analysis
Melting / freezing pt.:
175.5 °C
Atm. press.:
ca. 1 atm
Decomposition:
no
Sublimation:
no
Remarks on result:
other: Atmospheric pressure is not reported, however it is assumed that the test was performed at ambient pressure.

Preliminary Test

An endothermic heat effect was observed starting at 177.8 °C. After the experiment, the sample had lost about 61% of its mass and a black carbonized foam residue remained.

Main Tests

In order to determine the melting more precisely, further differential scanning calorimetry-runs were recorded between 120 °C and 220 °C with a heating rate of 10 °C/min. In the first main test run, the melting was observed at 175.3 °C, during the second main test run at 175.7 °C. During these runs, the samples lost about 3% of their mass and a brown melt remained in the sample cups.

Determination of the Melting Point

 

Heating Range

[°C]

Heating Rate

[°C/min]

Melting Point

[°C]

Melting Point

[K]

Preliminary Test

25 - 400

20

177.8

451.0

1stMain Test

120 - 220

10

175.3

448.5

2ndMain Test

120 – 220

10

175.7

448.9

Mean of melting point*:

175.5

448.7

 *The mean melting point was calculated from the two results of the Main Tests (onset point of the endothermic reaction).

 

Conclusions:
The melting point of the test item was determined to be 175.5 ± 0.5 °C. The study is considered to be adequate and reliable.
Executive summary:

The determination of the melting point/melting range of the test item was performed according to the OECD Guideline No. 102: “Melting point / melting range“, adopted July 27, 1995 by thermal analysis.

In a preliminary test done by differential scanning calorimetry, an endothermic heat effect was observed starting at 177.8 °C. In order to determine the melting more precisely, further differential scanning calorimetry-runs were recorded between 120 °C and 220 °C with a heating rate of 10 °C/min during the main test. In the first main test run, the melting was observed at 175.3 °C, during the second main test run at 175.7 °C.

The melting point of the test item was determined to be 175.5 ± 0.5 °C.

 

 

Description of key information

175.5 ± 0.5 °C,  OECD 102, DSC; thermal analysis, Kühne 2011. 

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
175.5 °C

Additional information

Only a single study conducted according to guidelines is available for this endpoint. The study is considered to be relevant, reliable (Klimisch 1) and adequate for the purposes of risk assessment, classification and labelling.