Cyclohexane-1,3-dione

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

15 Dec 2009 to 11 Feb 2010

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted to GLP and in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do no effect the quality of the relevant results.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2010

Report date:

2010

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 15-09-2009 Date of Signature: 26-11-2009

Type of method:

thermal analysis

Test material

Test material information

Constituent 1

Reference substance name:

Cyclohexane-1,3-dione

EC Number:

207-980-0

EC Name:

Cyclohexane-1,3-dione

Cas Number:

504-02-9

Molecular formula:

C6H8O2

IUPAC Name:

cyclohexane-1,3-dione

Details on test material:

- Name of test material (as cited in study report): 1,3 cyclohexane dione
- Substance type: Powder
- Physical state: Solid
- Analytical purity: 1,3 Cyclohexane Dione >97% W/W
- Impurities (identity and concentrations): Sodium Chloride 1%W/W Maximum
Water 0.5%W/W Maximum
- Composition of test material, percentage of components: 1,3 Cyclohexane Dione 99.2% W/W
Sodium Chloride 0.25%W/W
Water 0.4%W/W

- Purity test date: 18 November 2009
- Lot/batch No.: 184731091224
- Expiration date of the lot/batch: 18 May 2010
- Radiochemical purity (if radiolabelling): N/A
- Stability under test conditions: Stable
- Storage condition of test material: approximately 4 deg C in the dark

Results and discussion

Melting / freezing point

Melting / freezing pt.:

>= 372.5 - <= 373.5 K

Decomposition:

no

Sublimation:

no

Any other information on results incl. tables

Thermograms and thermographic data for Determinations 1 and 2 are shown in Figure 4.1 and Figure 4.2 and in the following tables respectively.

Figure4.1Thermogram – Determination 1 (see image below)

Table4.2Thermographic Data – Determination 1

Thermal Event	Interpretation	Temperature
		ºC	K
Endotherm	Melting temperature	100.26	373

Figure4.2Thermogram – Determination 2 (see image below)

Table4.3 Thermographic Data – Determination 2

Thermal Event	Interpretation	Temperature
		ºC	K
Endotherm	Melting temperature	100.20	373

Mean melting temperature: 373 ± 0.5 K:

Applicant's summary and conclusion

Conclusions:

The melting point of the test material has been determined to be 373+/-0.5K

Executive summary:

Melting/Freezing Temperature.373 ± 0.5 K, by differential scanning calorimetry, using ASTM E537-86, Method A1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008.