4-chlorobenzonitrile

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Endpoint:

biodegradation in water: screening test, other

Remarks:

dehalogenation

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods with acceptable restrictions

Qualifier:

no guideline followed

Principles of method if other than guideline:

4-chlorobenzonitrile was incubated with primary effluent of raw municipal sewage acclimated to non-chlorinated compounds at an initial concentration of 2mmol/L at 29 °C.The degradation of the test substacne was followed by photometric measurements of anorganic chloride that was released in connection with the decomposition of 4-chlorobenzonitrile.

GLP compliance:

no

Oxygen conditions:

aerobic

Inoculum or test system:

activated sludge, industrial, adapted

Duration of test (contact time):

2 d

Initial conc.:

2 mmol/L

Based on:

test mat.

Value:

>= 2.1 - <= 4.2

Sampling time:

2 d

Remarks on result:

not determinable

2.1 - 4.2 % organic chlorine were released as inorganic chlorine after 2 days by sewage sludge acclimated to various nonchlorinated compounds.

Validity criteria fulfilled:

not applicable

Interpretation of results:

other: 2.1 - 4.2 % degradation in 2 days

Conclusions:

Microorganisms are able to dehalogenate 4-chlorobenzonitrile.

Executive summary:

4-chlorobenzonitrile was incubated with primary effluent of raw municipal sewage acclimated to non-chlorinated compounds at an initial concentration of 2mmol/L at 29 °C. The degradation of the test substance was followed by photometric measurements of anorganic chlorine that was released in connection with the decomposition of 4-chlorobenzonitrile.

2.1 - 4.2 % organic chlorine were released as inorganic chlorine after 2 days by sewage sludge acclimated to various nonchlorinated compounds.

Due to the short incubation duration an interpretation of these results is difficult. It is not possible to differentiate whether the substance is not readily biodegradable or if biodegradation might start after a certain lag phase.

Description of key information

2.1 - 4.2 % organic chlorine were released as inorganic chlorine from 4-chlorobenzonitrile degradation after 2 days by sewage sludge acclimated to various nonchlorinated compounds.

Additional information

4-chlorobenzonitrile was incubated with primary effluent of raw municipal sewage acclimated to non-chlorinated compounds at an initial concentration of 2mmol/L at 29 °C. The degradation of the test substance was followed by photometric measurements of anorganic chlorine that was released in connection with the decomposition of 4-chlorobenzonitrile.

2.1 - 4.2 % organic chlorine were released as inorganic chlorine after 2 days by sewage sludge acclimated to various nonchlorinated compounds.

Due to the short incubation duration an interpretation of these results is difficult. It is not possible to differentiate whether the substance is not readily biodegradable or if biodegradation might start after a certain lag phase.