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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1962
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Abstract only available, data not accessible by the registrant

Data source

Reference
Reference Type:
secondary source
Title:
Initial submission to US EPA regarding the toxicity of Bromoaceti acid in rats and rabbits
Author:
US EPA
Year:
1992
Bibliographic source:
US EPA National Technical Information Service (NTIS), microfiche No. OTS0555280, Doc ID 88-92-0008963

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no data given
GLP compliance:
not specified
Test type:
other: 1 h inhalation screening
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Bromoacetic acid
EC Number:
201-175-8
EC Name:
Bromoacetic acid
Cas Number:
79-08-3
Molecular formula:
C2H3BrO2
IUPAC Name:
2-bromoacetic acid
Details on test material:
no data avaialble

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation: aerosol
Type of inhalation exposure:
not specified
Vehicle:
not specified
Details on inhalation exposure:
no details given
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
ca. 1 h
Concentrations:
2 to 200 mg/L
No. of animals per sex per dose:
No data
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
> 2 - < 200 mg/L air
Based on:
test mat.
Exp. duration:
1 h
Remarks on result:
other: no further data available

Applicant's summary and conclusion

Interpretation of results:
toxic
Remarks:
Migrated information class 3 Criteria used for interpretation of results: EU
Conclusions:
The data are of limited reliability as no details are given, but support the expected effects from a corrosive substance and the current classification as acute toxic class 3 by the inhalation route.
Executive summary:

The data are of limited reliability as no details are given, but support the expected effects from a corrosive substance and the current classification as acute toxic class 3 by the inhalation route.