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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

Based on reproduction, the 28-day NOEC for DTPA (free acid) in the crimson-spotted rainbowfish (Melanotaenia fluviatilis) was 100 mg/L.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
100 mg/L

Additional information

One chronic study for fish was available for DTPA (free acid). This study was well documented and met generally accepted scientific principles, and thus, was considered acceptable for assessment. In this study, adult male and female crimson-spotted rainbowfish (Melanotaenia fluviatilis) were exposed to DTPA in a static-renewal system for a period of 28 days and their reproduction, liver-somatic index, gonadal-somatic index, condition factor and EROD activity were assessed. There were no effects of parental DTPA exposure on apical endpoints, such as reproduction or condition factor, at the highest test concentration of 100 mg/L DTPA.