Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 249-109-7 | CAS number: 28629-66-5
Endpoint summary
Administrative data
Description of key information
Repeat dose oral toxicity data is not available for EC 249-109-7, but an OECD 407 study is available for an analogous substance and suitable for read across. NOAEL was 125 mg/kg/day for systemic toxicity.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- NOAEL
- 125 mg/kg bw/day
- Study duration:
- subacute
- Species:
- rat
Additional information
Repeated oral administration to rats for 28 consecutive days resulted in chemical-related effects at dose levels of 50 to 500 mg/kg/day. A dose level of 125 mg/kg/day was considered to be the NOAEL (no observable adverse effect level) for systemic toxicity.
Justification for classification or non-classification
In accordance with EU CLP Regulation (EC) No. 1272/2008, classification is not required for prolonged exposure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
