Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 273-227-8 | CAS number: 68953-84-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Using standard ready biodegradation test conditions, the test chemical displays negligible degradation.
1) Key: Biodegradation screening test: K2, per OECD 301F & GLP guideline; not readily biodegradable
2) Supporting: biodegradation screening test: K2, per OECD 301F & GLP guideline; not readily biodegradable
As a consequence the biodegradation potential of DAPD was further assessed in a number of inherent biodegradation studies. In these studies a surfactant is added to the test bottles in order to enhance the water solubility of the test substance, a lower concentration of test substance is used and an elevated sludge concentration when compared to a ready biodegradation test.
3) Supporting: Inherent biodegradation test: K2, per OECD 302C: no degradation
4) Supporting: Inherent biodegradation test: K1, per OECD 301B and 302C & GLP guideline; potential to degrade
5) Key: Inherent biodegradation test: K1, per OECD 301B and 302C & GLP guideline; inherent biodegradation observed
In these inherent biodegradation tests it was demonstrated that slow inherent biodegradation of DAPD does occur, yielding 23 to 37% of mineralisation after 56 -63 days. Furthermore, primary degradation of DAPD into water soluble metabolites / degradation products was found to occur much faster and lead to the complete removal of the parent compound from the test system within 28 days.
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