Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
in vivo mammalian cell study: DNA damage and/or repair
Study period:
2021-2022
Data waiving:
other justification
Justification for data waiving:
other:

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 489 (In vivo Mammalian Alkaline Comet Assay)
GLP compliance:
yes (incl. QA statement)
Type of assay:
mammalian comet assay

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N-diethylhydroxylamine
EC Number:
223-055-4
EC Name:
N,N-diethylhydroxylamine
Cas Number:
3710-84-7
Molecular formula:
C4H11NO
IUPAC Name:
N,N-diethylhydroxylamine
Test material form:
liquid

Test animals

Species:
rat
Strain:
Sprague-Dawley

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Applicant's summary and conclusion