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Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

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Administrative data

Link to relevant study record(s)

Description of key information

Eisenia andrei adults were exposed to 9 graded concentrations of N,N-diethylhydroxylamine for 28 days and cocoon/juveniles for another 28 day period. Adult survival and growth and number of juvenile produced per treatment were examined. No adult mortality occur. No significant diffence nor trend were observed for growth. Regarding juvenile production, a NOEC of 320 mg/kg soil dry wet was determined, as a decrease was observed at 1000 mg/kg soil dry weight.

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil macroorganisms:
320 mg/kg soil dw

Additional information

The study was performed using 9 concentrations ranging from 0.1 to 1000 mg/kg dry soil (4 replicates) and a control (8 replicates), following OECD 222 guideline protocol. In each replicate, 10 adult animals were exposed to the test item for 28 days in an artificial soil (except control group). After 28 days, the living adult animals were counted and weighted, and 28 days later, the number of juveniles produced was determined.

The highest concentrations showed statistical significant inhibition of reproduction (juvenile production) compared to the control. None of the adult animals were dead in any treatment or control after the first 28 days. Growth was not significantly different between treatments. A NOEC of 320 mg/kg soil dry weight was determined.