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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Type of information:
other: handbook data
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed physico-chemical data

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Journal of the American Chemical Society , 102(21), 6498-6503
Author:
Ball, Sheldon; Bruice, Thomas C
Year:
1980
Bibliographic source:
REAXYSFILE (previously Beilstein database)
Reference Type:
review article or handbook
Title:
Canadian journal of Chemistry 76(6), <1998>, 678 - 685;
Author:
Colthurst, Matthew J.; Kanagasooriam, Angeline J. S. S.; Wong, Michael S. O.; Contini, Christian; Williams, Andrew,
Year:
1998
Bibliographic source:
REAXYSFILE (previously Beilstein database)

Materials and methods

Principles of method if other than guideline:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N-diethylhydroxylamine
EC Number:
223-055-4
EC Name:
N,N-diethylhydroxylamine
Cas Number:
3710-84-7
Molecular formula:
C4H11NO
IUPAC Name:
N,N-diethylhydroxylamine

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
-0.75
Temp.:
30 °C
No.:
#2
pKa:
12.88
Temp.:
20 °C

Applicant's summary and conclusion

Conclusions:
the pKa of N,N-diethylhydroxylamine is 12.88 at 20°C