Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In this study there was no indication for a skin sensitizing potential of sodium perborate monohydrate. Also the degradation products (H2O2 and boron compounds) gave no concern for this endpoint.


Migrated from Short description of key information:
A possible sensitizing potential of sodium perborate monohydrate was tested in a study according to OECD Guideline 406 with Hartley albino guinea pigs. Under the conditions of this study, the test article is a non-sensitizer.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In this study there was no indication for a respiratory sensitizing potential of sodium perborate tetrahydrate.


Migrated from Short description of key information:
In a study with guinea pigs (inhalation exposure to sodium perborate tetrahydrate at 1 hour intervals for a total of 4 hours to 9 mg/m3 or for 1 hour per week for 6 consecutive weeks to 11 mg/m3; 6 weeks after the first exposure both exposure groups were challenged with the same concentration as above for 1 hour) there was no indication that the substance may cause respiratory sensitisation.

Justification for classification or non-classification