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EC number: 237-864-5 | CAS number: 14025-15-1
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1974
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Very limited reported study
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Examination of acute oral toxicity in mice after ip administration
- GLP compliance:
- no
- Limit test:
- no
Test material
- Reference substance name:
- Disodium [[N,N'-ethylenebis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',ON,ON']cuprate(2-)
- EC Number:
- 237-864-5
- EC Name:
- Disodium [[N,N'-ethylenebis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',ON,ON']cuprate(2-)
- Cas Number:
- 14025-15-1
- Molecular formula:
- C10H12CuN2O8.2Na
- IUPAC Name:
- Copper(2+) ion disodium 2-({2-[bis(carboxylatomethyl)amino]ethyl} (carboxylatomethyl)amino)acetate
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Name: Cutrilon (copper complex of Trilon B)
Appearance: solid
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- water
- Doses:
- not indicated
- No. of animals per sex per dose:
- not indicated
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- ca. 200 mg/kg bw
- Based on:
- test mat.
Any other information on results incl. tables
Clinical signs consisted of: dyspnoea, spasms, staggering gait, apathy, tearing, and animals were laying down.
At necropsy the animals did not show presence of substance accumulation.
Applicant's summary and conclusion
- Conclusions:
- The acute LD50 value via ip administration in mice is ca. 200 mg/kg bw.
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